پنجشنبه 30 شهريور 1396
به سایت مجله پزشکی دانشگاه علوم پزشکی و خدمات بهداشتی و درمانی تبریز خوش آمدید
   سپتامبر 21, 2017
   
   
     
  تعداد اعضاء : 2818 نفر
  بازدیدهای امروز :57 بار
  تعداد کل بازدیدها : 936129 بار
   
Volume: 39
Year: 2017
Month: 8
Subject Others
Title The effects of 8 weeks high intensity interval training on serum levels of TNF-α and insulin resistance index in obese men with type-2 diabetes
Authors Morteza Salimi Avansar;
Abstract Background: TNF-α is one of the Proinflammatory Cytokines mainly seen in Adipose tissue, Lymphocytes and Fibroblasts which increases in obese men and this increment is associated with insulin resistance and lots of metabolic diseases such as diabetes. The following research aimed to investigate the effect of HIIT exercises on changes of TNF-α and insulin resistance index. Methods: This experimentation included 24 obese men with type-2 diabetes who were randomly divided into two groups of Control and HIIT (n=12). The HIIT group performed regular exercises for 8 weeks long (3 sessions in every other days of a week= 30 training sessions in all). The assumptions of homogeneity of the slope of the regression line and also the linearity of the relationship between the scores before and after the practice is used and after the confirmation, Covariance analysis test is used (p<0/05). Results: HIIT training has a significant impact on TNF-α (p= <0.0001, f=41.058), Insulin Resistance (p=< 0.001, f= 51.825), Insulin (p= < 0.0001, f=51.785) and Glucose (p= 0.001, f= 13.177). Conclusion: It is concluded that HIIT trainings per 8 weeks has been able to reduce the plasma concentrations of TNF-α and insulin resistance index in obese men with type-2 diabetes. HIIT trainings have possibly restrained TNF-α by reducing the production of IL-6 and TNF-α itself has restrained the activity of insulin and some of its poor effectors too.
Key words: Tumor Necrosis Factor-Alpha, Insulin resistance index, High Intensity Interval Training (HIIT)
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ISSN 1608-5671 (Print)  

ISSN 2008-160X (Online)  
 
     
     
 

ضريب تأثير (IF) مجله پزشکی دانشگاه علوم پزشکی تبریز  در  پايگاه  استنادي علوم جهان اسلام (ISC)  

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