پنجشنبه 30 شهريور 1396
به سایت مجله پزشکی دانشگاه علوم پزشکی و خدمات بهداشتی و درمانی تبریز خوش آمدید
   سپتامبر 21, 2017
   
   
     
  تعداد اعضاء : 2818 نفر
  بازدیدهای امروز :62 بار
  تعداد کل بازدیدها : 936134 بار
   
Volume: 39
Year: 2017
Month: 8
Subject Others
Title Assessment of plasma and red blood cells fatty acid composition in boys with attention deficit hyperactivity disorder (ADHD)
Authors Parisa Mousavi; Bahram Pourghassem Gargari; Masoud Darabi; Ayyoub Malek; Shahrokh Amiri; Yalda Jabbari Moghaddam; Amir Mehdizadeh;
Abstract Background: Attention deficit hyperactivity disorder (ADHD) is one of the most common mental diseases in children. Fatty acids are important components of nerve cell myelin. Essential fatty acid deficiency leads to behavioral abnormalities similar to nervous disorders, such as ADHD. The purpose of this study was to determine the composition of fatty acids in plasma phospholipids and whole erythrocyte in the ADHD boys. Methods: This is a case-control study in which 36 boys with ADHD and 37 boys without ADHD -aged 6-12 years- were participated. ADHD children were diagnosed with clinical diagnosis and psychiatric questionnaires by a psychiatrist. Then fatty acids of plasma phospholipids and whole erythrocyte were extracted. Results: The mean content of sum of saturated fatty acids (P=0.004) and arachidonic acid (P<0.001) of plasma phospholipids were significantly lower and mean concentrations of oleic acid (P<0.001) and sum of monoenes (P<0.001) were significantly higher in the ADHD group compared to the control one. However in the total RBC, the mean concentrations of stearic acid (P=0.003), arachidonic acid (P=0.04) and α-linolenic (P=0.02) acid were significantly lower and the mean content of linoleic acid (P=0.01) was significantly higher in the ADHD group compared to the control one. Conclusion: Fatty acid composition of plasma phospholipids and RBC in the ADHD children differed from that of the non-ADHD children.
-Attention Deficit Hyperactivity Disorder, Fatty Acids, Red Blood Cell, Children
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ISSN 1608-5671 (Print)  

ISSN 2008-160X (Online)  
 
     
     
 

ضريب تأثير (IF) مجله پزشکی دانشگاه علوم پزشکی تبریز  در  پايگاه  استنادي علوم جهان اسلام (ISC)  

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