يکشنبه 4 اسفند 1398
به سایت مجله پزشکی دانشگاه علوم پزشکی و خدمات بهداشتی و درمانی تبریز خوش آمدید
   فيفرييه 23, 2020
   
   
     
  تعداد اعضاء : 3802 نفر
  بازدیدهای امروز :205 بار
  تعداد کل بازدیدها : 637200 بار
   
Volume: 41
Year: 2019
Month: 12
Subject Others
Title Evaluation of antibiotic resistance patterns in Staphylococcus aureus isolates collected from urinary tract infections in women referred to Shahid Beheshti educational and therapeutic center in Maragheh city, year 2016
Authors Zahra Yari; Saman Mahdavi; Shiva Khayati; Roghayeh Ghorbani; Alireza Isazadeh;
Abstract Background: Staphylococcus aureus is one of the important bacteria causing nosocomial infections. Nowdays, because of overuse of antibiotics, resistance is increasing and this problem has caused anxiety all over the world. The aim of this study was to evaluation of antibiotic resistance pattern in S.aureus isolates from urinary tract infections in Shahid Beheshti educational and therapeutic center in Maragheh city. Methods: In this cross sectional study, 100 S. aureus isolates were collected from patients suffering from urinary tract infections. After doing the biochemical tests for diagnosis of S. aureus, these isolates were identified as S.aureus with proliferation of thermonuclease species-specific gene (nuc) by polymerase chain reaction (PCR) method. Kirby-Bauer method was used for investigation of antibiotic resistance patterns in S. aureus isolates. Results: No significant difference in genotype frequencies was observed between the T2DM patients and normoglycemic controls. The rs7903146 (C/T) polymorphism odds ratios for CC and TC genotypes were 1.75 (95% CI, 0.63 to - 4.88; p=0.28) and 0.94 (95% CI, 0.49 to - 1.79; p = 0.84) compared with the TT genotype, respectively. The rs46522 (C/T) poly-morphism odds ratios for TT and TC genotypes were 1.41 (95% CI, 0.58 to - 3.42; p = 1.41) and 1.22 (95% CI, 0.64 to - 2.35; p = 1.22) compared with the CC genotype, respectively. Conclusion: Results of current study showed high antibiotic resistance in nosocomial S. aureus isolates. Therefore, antibiotics consumption should be avoided without proper prescription and unnecessary usage of routine antibiotics for showed be prevented.
Keyword: Staphylococcus aureus, Urinary tract infections, Antibiotic resistance, Maragheh
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ISSN 1608-5671 (Print)  

ISSN 2008-160X (Online)  
 
     
     
 

ضريب تأثير (IF) مجله پزشکی دانشگاه علوم پزشکی تبریز  در  پايگاه  استنادي علوم جهان اسلام (ISC)  

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